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从“烧钱研发”到“全球兑现”,这只创新药龙头走到临界点了吗?

发布于 2026-07-02

<section data-tool="mdnice编辑器" data-website="https://www.mdnice.com" style="margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 10px;padding-right: 10px;background-attachment: scroll;background-clip: border-box;background-color: rgba(0, 0, 0, 0);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;font-family: Optima, &#39;Microsoft YaHei&#39;, PingFangSC-regular, serif;font-size: 16px;color: rgb(0, 0, 0);line-height: 1.5em;word-spacing: 0em;letter-spacing: 0em;word-break: break-word;overflow-wrap: break-word;text-align: left;" data-pm-slice="0 0 []"><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">对于创新药企业来说,从“持续烧钱搞研发”到“靠商业化赚钱回血”,从来都是一道九死一生的坎。国内最早做PD-1的创新药企业君实生物,如今刚好站在了这道坎的临界线上。这份专业机构的深度研判,从财务质量、商业布局、风险压力等维度,给当前的君实生物做了一次全面的“体检”,结论里既有超出预期的惊喜,也点出了藏在财报里的陷阱,值得普通投资者认真琢磨。</span></p><h2 data-tool="mdnice编辑器" style="margin-top: 30px;margin-bottom: 15px;margin-left: 0px;margin-right: 0px;align-items: unset;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;flex-direction: unset;float: unset;height: auto;justify-content: center;line-height: 1.5em;overflow-x: unset;overflow-y: unset;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;text-align: left;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span style="font-size: 18px;color: rgb(130, 127, 196);line-height: 1.5em;letter-spacing: 0em;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;align-items: center;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;font-weight: bold;flex-direction: unset;float: unset;height: auto;justify-content: unset;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;overflow-x: unset;overflow-y: unset;text-align: left;text-indent: 0em;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span leaf="">一、财务质量体检:靓丽报表下,真实业绩到底是什么水平?</span></span></h2><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">很多投资者看创新药企业的财报,很容易被“亏损收窄”“现金流转正”这类关键词带动情绪,但专业分析往往会先剔除一次性干扰,还原企业真实的主营业务盈利能力。这份研报对君实生物2026年一季度的财报,就做了一次“法证级”的排雷梳理。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">从表面数据看,君实生物的2026年一季度确实足够亮眼:总营收7.26亿元,同比增长超过45%,核心产品特瑞普利单抗(商品名拓益)国内销售额达到6.23亿元,同比增长接近40%,更重要的是,公司经营性现金流首次转正,达到5785万元,这是很多投资者期待已久的信号。归母净利润账面亏损也只有不到2056万元,对比去年同期亏损超过2.35亿元,相当于亏损收窄了超过90%,看起来几乎就要扭亏为盈了。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">但拨开表象看本质,这次亏损大幅收窄高度依赖一次性的非经常性损益,而非主营业务本身已经盈利。数据显示,一季度君实生物总共获得1.23亿元非经常性损益,其中仅非流动资产处置一项就贡献了接近1.39亿元的收益——这部分是变卖资产得来的一次性收入,并不是卖药赚的钱,没办法持续。把这部分一次性收益剔除之后,君实生物的扣非归母净利润仍然亏损1.44亿元,也就是说,虽然主营业务确实在变好,但是还没有摸到盈亏平衡点,市场不能对一季度的账面数据过度解读。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">为了还原真实核心利润,研报也根据创新药企业的特点做了调整:由于君实生物对研发投入的会计处理非常审慎,所有在研项目投入几乎都做了费用化处理,没有通过开发支出资本化来调节利润,因此研发资本化调整项直接记为0,最终计算出来的真实核心利润和扣非归母净利润完全一致,2024年亏损12.9亿元,2025年亏损9.9亿元,2026年一季度亏损1.44亿元,整体亏损收窄的趋势非常明确,只是还没有实现正盈利。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">除了还原真实利润,研报还用应计利润率指标,评估了君实生物当前的盈余清澈度,也就是利润的含金量到底够不够。应计利润率的计算公式是(净利润-经营性现金流)/总资产,通过这个指标,可以看出公司有没有通过压货给渠道、提前确认收入等方式修饰业绩。计算结果显示:君实生物2024年应计利润率为+1.23%,2025年为-2.87%,2026年一季度为-0.55%,三个周期的应计利润率都处于极低或者负值区间,说明公司不存在过度应计修饰利润的问题。结合一季度经营性现金流首次转正,以及应收账款从2025年末的5.06亿元下降到2026年一季度末的4.6亿元,说明公司在销售端的货款回收速度明显加快,没有给渠道压货的情况,营收和利润的含金量其实是比较高的,整体财务健康度在持续改善。</span></p><h2 data-tool="mdnice编辑器" style="margin-top: 30px;margin-bottom: 15px;margin-left: 0px;margin-right: 0px;align-items: unset;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;flex-direction: unset;float: unset;height: auto;justify-content: center;line-height: 1.5em;overflow-x: unset;overflow-y: unset;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;text-align: left;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span style="font-size: 18px;color: rgb(130, 127, 196);line-height: 1.5em;letter-spacing: 0em;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;align-items: center;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;font-weight: bold;flex-direction: unset;float: unset;height: auto;justify-content: unset;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;overflow-x: unset;overflow-y: unset;text-align: left;text-indent: 0em;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span leaf="">二、商业生态梳理:“一超多强”格局下,第二曲线的成本优势有多强?</span></span></h2><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">对于创新药企业来说,光看当前的利润还不够,更要看未来的管线储备和平台价值——毕竟第一曲线把销售通路铺起来之后,新增管线能以多低的成本兑现,直接决定了企业的长期增长潜力。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">首先看价值创造能力,也就是大家常说的,公司赚的钱能不能覆盖资本成本。由于过去几年君实生物研发投入规模很大,销售网络还在扩张期,历史上资本回报率(ROIC)长期为负,远高于加权平均资本成本(WACC,研报测算为8.5%,也就是说只有ROIC超过8.5%,企业才是在创造价值,否则就是在毁灭价值)。2025年君实生物的ROIC测算为-11.4%,仍然在价值毁灭区间,但是到了2026年一季度,年化ROIC已经提升到-2.1%,ROIC和WACC之间的剪刀差正在快速收窄,价值创造的拐点越来越近。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">从管线布局来看,君实生物已经形成了非常清晰的“一超多强”格局:第一曲线就是特瑞普利单抗,目前已经完成了全球化的商业化通路铺设,已经在全球四十多个国家和地区获批上市,是国内最早实现海外多国商业化破局的PD-1产品之一。现在特瑞普利单抗的销售网络已经搭成,后续推新管线的时候,只需要付出极低的边际成本,就能给第二曲线输送现金流,这是很多初创biotech根本比不了的优势。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">更关键的是平台的技术同源性,君实生物现在的核心管线复用了现有平台的技术和产能,极大拉低了新增管线的开发成本:</span></p><ul style="list-style-type: disc;margin-top: 8px;margin-bottom: 8px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 25px;padding-right: 0px;color: rgb(0, 0, 0);" class="list-paddingleft-1"><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">目前市场关注度最高的PD-1/VEGF双抗JS207,本身就是以特瑞普利单抗为骨架设计的,抗PD-1的部分保留了原来的高亲和力,不需要重新筛选抗体分子,不仅大幅降低了技术迁移的成本,也降低了临床研发的不确定性,成功率比全新开发的分子高很多。</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">生产端的优势更明显,君实生物现在临港基地已经建成42000L产能,吴江基地有4500L产能,都是符合GMP标准的成熟产能,已经可以给新管线复用,新增管线的边际生产工艺开发成本,对比初创biotech直接降低了40%-50%,这个成本优势在创新药研发的内卷时代,是非常大的护城河。</span></section></li></ul><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">研报还通过熵值法TOPSIS做了护城河测算,君实生物的创新药链主贴近度得分为0.648,具备极强的稀缺性溢价,这个溢价主要就来自特瑞普利单抗的海外商业化率先破局,这是国内其他同赛道企业暂时还没有做到的。</span></p><h2 data-tool="mdnice编辑器" style="margin-top: 30px;margin-bottom: 15px;margin-left: 0px;margin-right: 0px;align-items: unset;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;flex-direction: unset;float: unset;height: auto;justify-content: center;line-height: 1.5em;overflow-x: unset;overflow-y: unset;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;text-align: left;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span style="font-size: 18px;color: rgb(130, 127, 196);line-height: 1.5em;letter-spacing: 0em;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;align-items: center;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;font-weight: bold;flex-direction: unset;float: unset;height: auto;justify-content: unset;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;overflow-x: unset;overflow-y: unset;text-align: left;text-indent: 0em;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span leaf="">三、极端压力测试:最坏情况发生,君实生物能扛得住吗?</span></span></h2><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">投资成长股,不仅要算对向上的空间,更要搞清楚向下的底线在哪里。为了评估极端情况君实生物的安全性,研报做了两类压力测试,给投资者划出了清晰的估值边界和安全垫。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">首先是用蒙特卡洛模拟做了10000次股价路径推演,基于君实生物过去252个交易日的历史波动率(年化波动率约42.6%)和行业贝塔值,推演未来120个交易日的股价概率分布,最终得到了三个关键位置:</span></p><ul style="list-style-type: disc;margin-top: 8px;margin-bottom: 8px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 25px;padding-right: 0px;color: rgb(0, 0, 0);" class="list-paddingleft-1"><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">95%置信区间的上沿,也就是强阻力位在45.8元;</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">50%置信分位数的估值中枢在32.5元;</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">5%置信区间的下沿,也就是强支撑位在21.1元。</span></section></li></ul><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">当前君实生物的股价是33.96元,刚好处于合理估值中枢32.5元的上方附近,也就是说当前股价已经消化了大部分已经披露的短期利好,没有被明显低估,也没有过度高估,整体处于合理区间的上端。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">除了股价的压力测试,研报还针对创新药企业最担心的两个风险点——医保降价和现金流断裂,做了极端情景测试:</span></p><ol style="list-style-type: decimal;margin-top: 8px;margin-bottom: 8px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 25px;padding-right: 0px;color: rgb(0, 0, 0);" class="list-paddingleft-1"><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><strong style="color: rgb(0, 0, 0);font-weight: bold;background-attachment: scroll;background-clip: border-box;background-color: rgba(0, 0, 0, 0);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;height: auto;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 3px;border-bottom-width: 3px;border-left-width: 3px;border-right-width: 3px;border-top-color: rgba(0, 0, 0, 0.4);border-bottom-color: rgba(0, 0, 0, 0.4);border-left-color: rgba(0, 0, 0, 0.4);border-right-color: rgba(0, 0, 0, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><span leaf="">医保降价极端测试</span></strong><span leaf="">:如果2026年底医保国谈,对拓益新增适应症和另一款产品君适达做极限降价,假设价格下调幅度超过市场预期,同时假设销量只增长1.5倍,测算下来,2027年的销售收入增长率会从原来的预期增速下滑,公司整体扭亏为盈的时间节点会从原来预期的2027年二季度,推迟到2028年三季度——哪怕发生极端降价,公司只是推迟盈利,不会出现基本面崩塌。</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><strong style="color: rgb(0, 0, 0);font-weight: bold;background-attachment: scroll;background-clip: border-box;background-color: rgba(0, 0, 0, 0);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;height: auto;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 3px;border-bottom-width: 3px;border-left-width: 3px;border-right-width: 3px;border-top-color: rgba(0, 0, 0, 0.4);border-bottom-color: rgba(0, 0, 0, 0.4);border-left-color: rgba(0, 0, 0, 0.4);border-right-color: rgba(0, 0, 0, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><span leaf="">现金流断裂测试</span></strong><span leaf="">:也就是我们常说的“现金跑道测试”,截至2026年一季度,君实生物的货币资金加上交易性金融资产合计有45.61亿元,流动负债里的短期借款只有7.29亿元。我们做最极端的假设:后续公司完全拿不到新的债务融资,同时主营业务完全不产生正向现金流,按照当前每个季度的真实亏损额和固定资本支出测算,现有的现金储备仍然可以支撑超过18个季度,也就是四年半的时间,完全足够覆盖新管线的临床读出周期,财务安全垫非常厚,根本不用担心短期会出现现金流问题。</span></section></li></ol><h2 data-tool="mdnice编辑器" style="margin-top: 30px;margin-bottom: 15px;margin-left: 0px;margin-right: 0px;align-items: unset;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;flex-direction: unset;float: unset;height: auto;justify-content: center;line-height: 1.5em;overflow-x: unset;overflow-y: unset;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;text-align: left;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span style="font-size: 18px;color: rgb(130, 127, 196);line-height: 1.5em;letter-spacing: 0em;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;align-items: center;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;font-weight: bold;flex-direction: unset;float: unset;height: auto;justify-content: unset;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;overflow-x: unset;overflow-y: unset;text-align: left;text-indent: 0em;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span leaf="">四、微观资金博弈:当前资金是怎么看待君实生物的?</span></span></h2><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">估值最终是要靠资金买出来的,研报也从市场微观结构的角度,分析了当前君实生物的资金状态和估值转移概率。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">研报把君实生物的估值分成了三个状态:PB低于4.5倍为低估、PB在4.5倍到7.0倍之间为合理、PB高于7倍为高估,当前君实生物的PB约为5.9倍,刚好处于合理估值的状态2。基于过去三年的周频数据,推演出来未来六个月的估值状态转移概率是这样的:</span></p><ul style="list-style-type: disc;margin-top: 8px;margin-bottom: 8px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 25px;padding-right: 0px;color: rgb(0, 0, 0);" class="list-paddingleft-1"><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">维持当前合理区间的概率是70%,也就是大概率会继续在当前区间震荡;</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">向低估值区间回落的概率是18%,向下的风险其实不大;</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">如果新药临床数据读出超预期,触发估值向高估区间跃迁的概率是12%,也就是有一成多的概率出现估值抬升。</span></section></li></ul><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">从资金的叙事轨迹来看,当前的资金路径也非常清晰:如果后续出现海外获批落地、国内销售超预期这类利好,会吸引头部量化资金和外资北向资金流入,推动多头动能增强,带动PB向高估区间转移;但如果出现散户对医保降价的过度担忧、博弈情绪升温,就会导致股价波动加大,资金会在30元到38元这个区间震荡整固,和当前的估值状态匹配。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">最后看杠杆水平,截至研报出具日,君实生物的融券余额占自由流通市值的比例只有1.12%,处于很低的位置,融资买入额占比也保持平稳,融资买入偿还比的Z分数只有0.45,说明市场上没有出现极端的散户杠杆资金拥挤的情况,不存在因为强制平仓或者抱团瓦解引发的股价崩塌风险,向下的波动风险整体可控。</span></p><h2 data-tool="mdnice编辑器" style="margin-top: 30px;margin-bottom: 15px;margin-left: 0px;margin-right: 0px;align-items: unset;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;flex-direction: unset;float: unset;height: auto;justify-content: center;line-height: 1.5em;overflow-x: unset;overflow-y: unset;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;text-align: left;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span style="font-size: 18px;color: rgb(130, 127, 196);line-height: 1.5em;letter-spacing: 0em;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;align-items: center;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;font-weight: bold;flex-direction: unset;float: unset;height: auto;justify-content: unset;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;overflow-x: unset;overflow-y: unset;text-align: left;text-indent: 0em;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span leaf="">五、跨期估值定价:当前34元的股价,到底贵不贵?</span></span></h2><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">研报最后对君实生物做了业绩前瞻和多维估值,给当前股价做了一次定价。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">首先是业绩预测,结合2026年一季度的销售势头,以及拓益新增两个适应症、君适达正式执行新版医保目录带来的放量效应,研报给出的前瞻业绩是:</span></p><ul style="list-style-type: disc;margin-top: 8px;margin-bottom: 8px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 25px;padding-right: 0px;color: rgb(0, 0, 0);" class="list-paddingleft-1"><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">2026年全年预计实现营收32.5亿元,营收增速29.9%,净利润预计亏损1.5亿元,扣非净利润预计亏损4.8亿元——这里需要注意,2026年全年不会再有一季度那样的大额资产处置收益,所以账面仍然维持小幅亏损,但是核心亏损已经大幅收窄。</span></section></li><li><section style="margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;font-weight: normal;"><span leaf="">2027年全年预计实现营收43.8亿元,营收增速34.8%,净利润预计盈利2.1亿元,扣非净利润预计盈利1.2亿元,也就是2027年可以实现扣非后的全面盈利,正式跨过盈亏平衡点。</span></section></li></ul><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">接下来研报用反向工程,推导了当前估值隐含的长期增长率:当前君实生物的企业价值EV大约是320亿元,WACC按8.5%计算,反向推导出来当前估值隐含的2027年到2035年自由现金流复合增长率大约是7.7%。对于一家已经实现多国商业化突破,同时有多款处于临床后期的管线(比如JS207、JS212、Tifcemalimab)的创新药龙头来说,7.7%的长期增长预期其实是偏低的,也就是说当前估值隐含的预期并不高,反而具备一定的安全边际。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">最后做了同业对比,创新药企业在完全盈利之前,市场一般用市销率P/S和市净率P/B做对比,我们把君实生物和国内同赛道的头部企业对比来看:</span></p><section data-tool="mdnice编辑器" style="margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;overflow-x: auto;"><table style="display:table;text-align:left;min-width:322px;"><thead><tr><th data-colwidth="108" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.5em;letter-spacing: 0em;text-align: left;font-weight: bold;background: none left top / auto no-repeat scroll padding-box border-box rgb(240, 240, 240);height: auto;border-style: solid;border-width: 1px;border-color: rgba(204, 204, 204, 0.4);border-radius: 0px;padding: 5px 10px;min-width: 85px;"><section><span leaf="">企业</span></section></th><th data-colwidth="112" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.5em;letter-spacing: 0em;text-align: left;font-weight: bold;background: none left top / auto no-repeat scroll padding-box border-box rgb(240, 240, 240);height: auto;border-style: solid;border-width: 1px;border-color: rgba(204, 204, 204, 0.4);border-radius: 0px;padding: 5px 10px;min-width: 85px;"><section><span leaf="">2026E P/S</span></section></th><th data-colwidth="77" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.5em;letter-spacing: 0em;text-align: left;font-weight: bold;background: none left top / auto no-repeat scroll padding-box border-box rgb(240, 240, 240);height: auto;border-style: solid;border-width: 1px;border-color: rgba(204, 204, 204, 0.4);border-radius: 0px;padding: 5px 10px;min-width: 85px;"><section><span leaf="">P/B</span></section></th><th style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.5em;letter-spacing: 0em;text-align: left;font-weight: bold;background: none left top / auto no-repeat scroll padding-box border-box rgb(240, 240, 240);height: auto;border-style: solid;border-width: 1px;border-color: rgba(204, 204, 204, 0.4);border-radius: 0px;padding: 5px 10px;min-width: 85px;"><section><span leaf="">核心优势</span></section></th></tr></thead><tbody><tr style="color: rgb(0, 0, 0);background-attachment: scroll;background-clip: border-box;background-color: rgb(255, 255, 255);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;height: auto;"><td data-colwidth="108" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">君实生物</span></section></td><td data-colwidth="112" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">10.7</span></section></td><td data-colwidth="77" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">5.9</span></section></td><td style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">PD-1海外获批,有多个后期管线</span></section></td></tr><tr style="color: rgb(0, 0, 0);background-attachment: scroll;background-clip: border-box;background-color: rgb(248, 248, 248);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;height: auto;"><td data-colwidth="108" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">信达生物</span></section></td><td data-colwidth="112" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">8.9</span></section></td><td data-colwidth="77" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">6.8</span></section></td><td style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">PD-1商业化成熟</span></section></td></tr><tr style="color: rgb(0, 0, 0);background-attachment: scroll;background-clip: border-box;background-color: rgb(255, 255, 255);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;height: auto;"><td data-colwidth="108" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">百济神州</span></section></td><td data-colwidth="112" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">7.6</span></section></td><td data-colwidth="77" style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">7.2</span></section></td><td style="padding-top: 5px;padding-right: 10px;padding-bottom: 5px;padding-left: 10px;min-width: 85px;border-top-style: solid;border-bottom-style: solid;border-left-style: solid;border-right-style: solid;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgba(204, 204, 204, 0.4);border-bottom-color: rgba(204, 204, 204, 0.4);border-left-color: rgba(204, 204, 204, 0.4);border-right-color: rgba(204, 204, 204, 0.4);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-right-radius: 0px;border-bottom-left-radius: 0px;"><section><span leaf="">全球化大单品管线丰富</span></section></td></tr></tbody></table></section><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">对比下来,君实生物的P/B处于行业中游偏下的水平,虽然2026E的P/S比另外两家略高,但这主要是因为2025年拓益的医保适应症范围比较窄,影响了当年的营收,随着2026年拓益12项适应症全面纳入医保,加上皮下注射制剂JS001sc的获批预期,后续营收增速会加快,远期的P/S会快速降下来,估值并不会比同业更贵。</span></p><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">当然,研报也提示了潜在风险:创新药研发本身存在非常大的不确定性,如果核心新管线的临床数据不及预期,可能会影响估值,另外海外商业化的推进也可能因为海外审批、渠道拓展等因素,出现不及预期的情况,投资者需要注意这部分风险。</span></p><h2 data-tool="mdnice编辑器" style="margin-top: 30px;margin-bottom: 15px;margin-left: 0px;margin-right: 0px;align-items: unset;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;flex-direction: unset;float: unset;height: auto;justify-content: center;line-height: 1.5em;overflow-x: unset;overflow-y: unset;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;text-align: left;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span style="font-size: 18px;color: rgb(130, 127, 196);line-height: 1.5em;letter-spacing: 0em;padding-top: 0px;padding-bottom: 0px;padding-left: 0px;padding-right: 0px;align-items: center;background-attachment: scroll;background-clip: border-box;background-color: transparent;background-image: none;background-origin: padding-box;background-position-x: 0%;background-position-y: 0%;background-repeat: no-repeat;background-size: auto;border-top-style: none;border-bottom-style: none;border-left-style: none;border-right-style: none;border-top-width: 1px;border-bottom-width: 1px;border-left-width: 1px;border-right-width: 1px;border-top-color: rgb(0, 0, 0);border-bottom-color: rgb(0, 0, 0);border-left-color: rgb(0, 0, 0);border-right-color: rgb(0, 0, 0);border-top-left-radius: 0px;border-top-right-radius: 0px;border-bottom-left-radius: 0px;border-bottom-right-radius: 0px;box-shadow: none;display: flex;font-weight: bold;flex-direction: unset;float: unset;height: auto;justify-content: unset;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;overflow-x: unset;overflow-y: unset;text-align: left;text-indent: 0em;text-shadow: none;transform: none;width: auto;-webkit-box-reflect: unset;"><span leaf="">总结:当前君实生物处于什么位置?</span></span></h2><p data-tool="mdnice编辑器" style="color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: 0em;text-align: left;text-indent: 0em;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 8px;padding-bottom: 8px;padding-left: 0px;padding-right: 0px;"><span leaf="">总结下来,当前君实生物正处于从“高烈度研发失血期”向“全球化商业化兑现期”过渡的临界状态:主营业务改善趋势明确,现金流首次转正,盈利拐点越来越近,凭借第一曲线的全球通路和成熟平台,第二管线的开发成本远低于行业平均,财务安全垫很厚,当前估值隐含的增长预期不高,具备一定的安全边际。但投资者也需要清楚,当前主营业务还没有实现盈利,一季度的靓丽账面数据有一次性资产处置的贡献,当前股价已经消化了大部分短期利好,后续的估值弹性,主要取决于JS207、JS212这些第二曲线管线的临床数据读出,值得投资者持续跟踪这两个管线的进展。</span></p></section><hr style="border-style: solid;border-width: 1px 0 0;border-color: rgba(0,0,0,0.1);-webkit-transform-origin: 0 0;-webkit-transform: scale(1, 0.5);transform-origin: 0 0;transform: scale(1, 0.5);" /><section data-tool="mdnice编辑器" data-website="https://www.mdnice.com" style="margin-top: 0px;margin-bottom: 0px;margin-left: 0px;margin-right: 0px;padding-top: 0px;padding-bottom: 0px;padding-left: 10px;padding-right: 10px;background-attachment: scroll;background-clip: border-box;background-color: rgba(0, 0, 0, 0);background-image: none;background-origin: padding-box;background-position-x: left;background-position-y: top;background-repeat: no-repeat;background-size: auto;width: auto;font-family: Optima, &#39;Microsoft YaHei&#39;, PingFangSC-regular, serif;font-size: 16px;color: rgb(0, 0, 0);line-height: 1.5em;word-spacing: 0em;letter-spacing: 0em;word-break: break-word;overflow-wrap: break-word;text-align: left;" data-pm-slice="0 0 []"><p data-layout-id="58" data-pm-slice="0 0 []" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px 0px 24px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;color: rgba(0, 0, 0, 0.9);font-family: &quot;PingFang SC NEW&quot;, system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: 0.544px;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;white-space: normal;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);line-height: 1.8;"><span leaf="" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;"><span textstyle="" style="color: rgba(0, 0, 0, 0.9);">更多深度资讯,请在抖音搜索“禾略财讯”</span></span></p><section data-layout-id="59" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px 0px 24px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgba(0, 0, 0, 0.9);font-family: &quot;PingFang SC NEW&quot;, system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;white-space: normal;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);text-align: center;line-height: 1.8;"><section nodeleaf="" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px 0px 24px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;text-align: center;font-size: 17px;font-weight: 400;color: rgba(0, 0, 0, 0.9);line-height: 1.8;"><img data-src="https://mmbiz.qpic.cn/mmbiz_jpg/9alt9LFC5gyibVSBDRib1YCtmyI9qEZnHK2fbdhScpPibP7RJUaEXfr6w4qZy5z0WZ1azAcOWIib19eIfbDm7T8WfYsNUm21ovD32B6ZCKxiaJKg/640?wx_fmt=jpeg&amp;from=appmsg&amp;watermark=1&amp;wxfrom=5&amp;wx_lazy=1&amp;tp=webp#imgIndex=0" alt="图片" class="rich_pages wxw-img" data-ratio="0.562962962962963" data-s="300,640" data-type="jpeg" data-w="1080" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;vertical-align: bottom;height: auto !important;visibility: visible !important;width: 676.969px !important;" type="block" data-imgfileid="100048501" data-aistatus="1" /></section></section><p data-layout-id="60" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px 0px 24px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;color: rgba(0, 0, 0, 0.9);font-family: &quot;PingFang SC NEW&quot;, system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: 0.544px;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;white-space: normal;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);line-height: 1.8;"><span leaf="" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;"><span textstyle="" style="color: rgba(0, 0, 0, 0.9);">免费体验:打开浏览器,https://schat.urasr.com</span></span></p><section data-layout-id="61" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px 0px 24px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgba(0, 0, 0, 0.9);font-family: &quot;PingFang SC NEW&quot;, system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;white-space: normal;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);text-align: center;line-height: 1.8;"><section nodeleaf="" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px 0px 24px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;text-align: center;font-size: 17px;font-weight: 400;color: rgba(0, 0, 0, 0.9);line-height: 1.8;"><img data-src="https://mmbiz.qpic.cn/mmbiz_png/9alt9LFC5gwIygW6VLE77t57piazkFmyJiboVvUWyO9v167yNH7E12N1ia5RQb0DN60pcfQZuOaKSRF1Knw6eaMiaXjO72ibLs3MdGQRs96kYQdI/640?wx_fmt=png&amp;from=appmsg&amp;watermark=1&amp;wxfrom=5&amp;wx_lazy=1&amp;tp=webp#imgIndex=1" alt="图片" class="rich_pages wxw-img" data-ratio="0.5640625" data-s="300,640" data-type="png" data-w="640" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;vertical-align: bottom;height: auto !important;visibility: visible !important;width: 640px !important;" type="block" data-imgfileid="100048500" data-aistatus="1" /></section></section></section><section><span leaf=""><br /></span></section><p style="display: none;"><mp-style-type data-value="3"></mp-style-type></p>

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